The cell death forum

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The endpoints used to evaluate neurotoxicity of drugs and chemicals are multiple and reflect the complexity of the nervous system. In many instances, loss of function can result from a temporary impairment of synaptic activity. However, exposure to some neurotoxic conditions may eventually lead to neuronal loss and be fatal to the organism. Execution of the apoptotic program seems to be the mec...

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ژورنال

عنوان ژورنال: Cell Death & Differentiation

سال: 2009

ISSN: 1350-9047,1476-5403

DOI: 10.1038/cdd.2008.180